Stir Bar Sorptive Extraction (SBSE) coupled with gas chromatography-mass spectrometry and olfactory detection (GC-MS/O) allows for separation and identifi cation of aroma compounds in complex sample matrices with minimal sample preparation time. Aroma Dilution Analysis (ADA) is a solvent-free approach of Aroma Extract Dilution Analysis (AEDA) which employs a GC inlet system to split the carrier gas fl ow and thereby the injected sample to a desired ratio. The approach of ADA has been applied to direct immersion SBSE of bourbon samples for determination of fl avor dilution (FD) factors and identifi cation of key aroma-active compounds.

Plastics, micro- and nanoplastics pollution in oceans, lakes and other water sources is a well-documented issue. Uptake of these particles by shellfish and fish is one avenue for the pollutants to enter the food chain and cause possible adverse effects. Microand nanoplastics are commonly used in commercially available products as abrasives. They end up in the environment through drain disposal since they are not always efficiently removed in the waste water treatment process.

Raman and infrared spectroscopy are often used for identification, but dyes used in the plastic material can sometimes hamper identification using these techniques.

The manual preparation of calibration standards and QC samples is part of the daily activities of laboratories that analyze food samples for contaminants. The accurate ...

The number of cannabis containing products, such as extracts, tinctures, edibles, waxes and oils, available in the United States have increased significantly due ...

The number of cannabis containing products, such as extracts, tinctures, edibles, waxes and oils, available in the United States has increased significantly due to ...

The manual transfer of liquid samples is part of daily activities throughout the analytical laboratory. The accurate and precise transfer of liquid samples ...

The in vitro metabolic stability of potential drug candidates is routinely examined at an early stage of drug discovery. Metabolic stability is a simple, well-established screening technique used to predict the in vivo hepatic clearance of a drug based on due to metabolism. With the ever-increasing chemical libraries, today’s drug metabolism and pharmacokinetic (DMPK) laboratories are constantly being asked to increase the number of molecules that can be assayed to decrease the time needed to identify lead drug candidates.

Direct thermal extraction (DTE) is a thermal desorption technique in which a small amount of sample, typically 10-50 mg, is placed in an empty fritted thermal desorption tube or into a small vial (μ-vial) within an empty thermal desorption tube. The sample is then heated in a thermal desorption unit under a fl ow of inert gas, in order to release volatile and semi-volatile compounds. The analytes are trapped and fi nally determined by GC/MS. DTE requires little sample preparation and can be used for trace analysis of volatile and semivolatile organic compounds in solid or liquid samples.

Antibiotics are a class of antimicrobial veterinary drugs widely used to control disease in food producing animals including egg laying chickens. However, ...

This study describes the use of the GERSTEL MultiPurpose Sampler (MPS) fitted with a Thermal Desorption Unit (TDU) and a Cooled Injection System (CIS 4) PTV-type Inlet ...